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Outbred ICR/CD1 mice display more severe neuroinflammation mediated by microglial TLR4/CD14 activation than inbred C57Bl/6 mice

Neuroinflammation mediated by microglia is a pathological hallmark of many CNS disorders. Cell lines derived from inbred C57Bl/6 and outbred ICR/CD1 mice (BV2 and N9 respectively), are often used to study microglial inflammatory activities. Although many studies demonstrate different responses of th...

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Detalhes bibliográficos
Main Authors: Nikodemova, Maria, Watters, Jyoti J
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156380/
https://ncbi.nlm.nih.gov/pubmed/21683771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2011.06.006
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