Oligodendroglial TNFR2 Mediates Membrane TNF-Dependent Repair in Experimental Autoimmune Encephalomyelitis by Promoting Oligodendrocyte Differentiation and Remyelination

Tumor necrosis factor (TNF) is associated with the pathophysiology of various neurological disorders, including multiple sclerosis. It exists as a transmembrane form tmTNF, signaling via TNF receptor 2 (TNFR2) and TNFR1, and a soluble form, solTNF, signaling via TNFR1. Multiple sclerosis is associat...

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Pubblicato in:J Neurosci
Autori principali: Madsen, Pernille M., Motti, Dario, Karmally, Shaffiat, Szymkowski, David E., Lambertsen, Kate Lykke, Bethea, John R., Brambilla, Roberta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854972/
https://ncbi.nlm.nih.gov/pubmed/27147664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0211-16.2016
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