Oligodendroglial TNFR2 Mediates Membrane TNF-Dependent Repair in Experimental Autoimmune Encephalomyelitis by Promoting Oligodendrocyte Differentiation and Remyelination

Tumor necrosis factor (TNF) is associated with the pathophysiology of various neurological disorders, including multiple sclerosis. It exists as a transmembrane form tmTNF, signaling via TNF receptor 2 (TNFR2) and TNFR1, and a soluble form, solTNF, signaling via TNFR1. Multiple sclerosis is associat...

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Publicat a:J Neurosci
Autors principals: Madsen, Pernille M., Motti, Dario, Karmally, Shaffiat, Szymkowski, David E., Lambertsen, Kate Lykke, Bethea, John R., Brambilla, Roberta
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854972/
https://ncbi.nlm.nih.gov/pubmed/27147664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0211-16.2016
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