Deficiency of Isoprenylcysteine Carboxyl Methyltransferase (ICMT) Leads to Progressive Loss of Photoreceptor Function

Retinal neurons use multiple strategies to fine-tune visual signal transduction, including post-translational modifications of proteins, such as addition of an isoprenyl lipid to a carboxyl-terminal cysteine in proteins that terminate with a “CAAX motif.” We previously showed that RAS converting enz...

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Vydáno v:J Neurosci
Hlavní autoři: Christiansen, Jeffrey R., Pendse, Nachiket D., Kolandaivelu, Saravanan, Bergo, Martin O., Young, Stephen G., Ramamurthy, Visvanathan
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854971/
https://ncbi.nlm.nih.gov/pubmed/27147662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0176-16.2016
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