Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice

We tested the hypothesis that supplementation of nicotinamide mononucleotide (NMN), a key NAD (+) intermediate, increases arterial SIRT1 activity and reverses age‐associated arterial dysfunction and oxidative stress. Old control mice (OC) had impaired carotid artery endothelium‐dependent dilation (E...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: de Picciotto, Natalie E., Gano, Lindsey B., Johnson, Lawrence C., Martens, Christopher R., Sindler, Amy L., Mills, Kathryn F., Imai, Shin‐ichiro, Seals, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854911/
https://ncbi.nlm.nih.gov/pubmed/26970090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12461
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados