Genetic effect of chemotherapy exposure in children of testicular cancer survivors

BACKGROUND: Cancer survivors express anxiety that chemotherapy exposure may lead to transmissible genetic damage in post-treatment children. Preclinical models suggest chemotherapy exposure may result in considerable genomic alterations in post-exposure progeny. Epidemiological studies have not demo...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Kryukov, Gregory V., Bielski, Craig M., Samocha, Kaitlin, Fromer, Menachem, Seepo, Sara, Gentry, Carleen, Neale, Benjamin, Garraway, Levi A., Sweeney, Christopher, Taplin, Mary-Ellen, Van Allen, Eliezer M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854770/
https://ncbi.nlm.nih.gov/pubmed/26631610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2317
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