The presence of LC3B puncta and HMGB1 expression in malignant cells correlate with the immune infiltrate in breast cancer

Several cell-intrinsic alterations have poor prognostic features in human breast cancer, as exemplified by the absence of MAP1LC3B/LC3B (microtubule-associated protein 1 light chain 3 β)-positive puncta in the cytoplasm (which indicates reduced autophagic flux) or the loss of nuclear HMGB1 expressio...

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Gepubliceerd in:Autophagy
Hoofdauteurs: Ladoire, Sylvain, Enot, David, Senovilla, Laura, Ghiringhelli, François, Poirier-Colame, Vichnou, Chaba, Kariman, Semeraro, Michaela, Chaix, Marie, Penault-Llorca, Frédérique, Arnould, Laurent, Poillot, Marie Laure, Arveux, Patrick, Delaloge, Suzette, Andre, Fabrice, Zitvogel, Laurence, Kroemer, Guido
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2016
Onderwerpen:
Clinical Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854557/
https://ncbi.nlm.nih.gov/pubmed/26979828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1154244
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