Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure

Sphingomyelin is an essential cellular lipid that traffics between plasma membrane and intracellular organelles until directed to lysosomes for SMPD1 (sphingomyelin phosphodiesterase 1)-mediated degradation. Inactivating mutations in the SMPD1 gene result in Niemann-Pick diseases type A and B charac...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Corcelle-Termeau, Elisabeth, Vindeløv, Signe Diness, Hämälistö, Saara, Mograbi, Baharia, Keldsbo, Anne, Bräsen, Jan Hinrich, Favaro, Elena, Adam, Dieter, Szyniarowski, Piotr, Hofman, Paul, Krautwald, Stefan, Farkas, Thomas, Petersen, Nikolaj H.T., Rohde, Mikkel, Linkermann, Andreas, Jäättelä, Marja
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854555/
https://ncbi.nlm.nih.gov/pubmed/27070082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1159378
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados