Genome-wide methylation analysis of retrocopy-associated CpG islands and their genomic environment

Gene duplication by retrotransposition, i.e., the reverse transcription of an mRNA and integration of the cDNA into the genome, is an important mechanism in evolution. Based on whole-genome bisulfite sequencing of monocyte DNA, we have investigated the methylation state of all CpG islands (CGIs) ass...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Grothaus, Katrin, Kanber, Deniz, Gellhaus, Alexandra, Mikat, Barbara, Kolarova, Julia, Siebert, Reiner, Wieczorek, Dagmar, Horsthemke, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854546/
https://ncbi.nlm.nih.gov/pubmed/26890210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2016.1145330
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