Melanin targets LC3-associated phagocytosis (LAP): A novel pathogenetic mechanism in fungal disease

Intracellular swelling of conidia of the major human airborne fungal pathogen Aspergillus fumigatus results in surface exposure of immunostimulatory pathogen-associated molecular patterns (PAMPs) and triggers activation of a specialized autophagy pathway called LC3-associated phagocytosis (LAP) to p...

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Bibliographische Detailangaben
Veröffentlicht in:Autophagy
Hauptverfasser: Chamilos, Georgios, Akoumianaki, Tonia, Kyrmizi, Irene, Brakhage, Axel, Beauvais, Anne, Latge, Jean-Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
Schlagworte:
Autophagic Puncta
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854543/
https://ncbi.nlm.nih.gov/pubmed/27028978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1157242
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