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Neural effects of gut‐ and brain‐derived glucagon‐like peptide‐1 and its receptor agonist
Glucagon‐like peptide‐1 (GLP‐1) is derived from both the enteroendocrine L cells and preproglucagon‐expressing neurons in the nucleus tractus solitarius (NTS) of the brain stem. As GLP‐1 is cleaved by dipeptidyl peptidase‐4 yielding a half‐life of less than 2 min, it is plausible that the gut‐derive...
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| Publicado no: | J Diabetes Investig |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4854507/ https://ncbi.nlm.nih.gov/pubmed/27186358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12464 |
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