Glucagon‐like peptide‐1 and cholecystokinin production and signaling in the pancreatic islet as an adaptive response to obesity

Precise control of blood glucose is dependent on adequate β‐cell mass and function. Thus, reductions in β‐cell mass and function lead to insufficient insulin production to meet demand, and result in diabetes. Recent evidence suggests that paracrine signaling in the islet might be important in obesit...

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Bibliographic Details
Published in:J Diabetes Investig
Main Authors: Linnemann, Amelia K, Davis, Dawn Belt
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Proceedings of INCRETIN 2015, A Symposium Celebrating the 45th Anniversary of the Discovery of GIP, 29–31 July 2015, Vancouver, Canada. This publication has been supported by: The Local Organizing Committee of INCRETIN 2015
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854504/
https://ncbi.nlm.nih.gov/pubmed/27186355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12465
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