The Caenorhabditis elegans Protein FIC-1 Is an AMPylase That Covalently Modifies Heat-Shock 70 Family Proteins, Translation Elongation Factors and Histones

Protein AMPylation by Fic domain-containing proteins (Fic proteins) is an ancient and conserved post-translational modification of mostly unexplored significance. Here we characterize the Caenorhabditis elegans Fic protein FIC-1 in vitro and in vivo. FIC-1 is an AMPylase that localizes to the nuclea...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Truttmann, Matthias C., Cruz, Victor E., Guo, Xuanzong, Engert, Christoph, Schwartz, Thomas U., Ploegh, Hidde L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854385/
https://ncbi.nlm.nih.gov/pubmed/27138431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006023
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