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Over-expression of the constitutive AMPylase FIC-1(E274G) does not deplete cellular ATP pools in C. elegans

Protein AMPylation has emerged as a posttranslational protein modification regulating cellular proteostasis. AMPylation is conferred by Fic AMPylases, which catalyze the covalent attachment of AMP to target proteins at the expense of ATP. Over-expression of constitutive-active Fic AMPylases is toxic...

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Bibliographische Detailangaben
Veröffentlicht in:MicroPubl Biol
Hauptverfasser: Champion, Margaret, Truttmann, Matthias C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Caltech Library 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233689/
https://ncbi.nlm.nih.gov/pubmed/34189425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17912/micropub.biology.000409
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