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Caged [(18)F]FDG Glycosylamines for Imaging Acidic Tumor Microenvironments Using Positron Emission Tomography

Solid tumors are hypoxic with altered metabolism, resulting in secretion of acids into the extracellular matrix and lower relative pH, a feature associated with local invasion and metastasis. Therapeutic and diagnostic agents responsive to this microenvironment may improve tumor-specific delivery. T...

詳細記述

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書誌詳細
出版年:Bioconjug Chem
主要な著者: Flavell, Robert R., Truillet, Charles, Regan, Melanie K., Ganguly, Tanushree, Blecha, Joseph E., Kurhanewicz, John, VanBrocklin, Henry F., Keshari, Kayvan R., Chang, Christopher J., Evans, Michael J., Wilson, David M.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854293/
https://ncbi.nlm.nih.gov/pubmed/26649808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00584
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