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Hyperpolarized [1-(13)C]Dehydroascorbate MR Spectroscopy in a Murine Model of Prostate Cancer: Comparison with (18)F-FDG PET
Reduction and oxidation (redox) chemistry is increasingly implicated in cancer pathogenesis. To interrogate the redox status of prostate tumors noninvasively, we developed hyperpolarized [1-(13)C]dehydroascorbate ((13)C-DHA), the oxidized form of vitamin C, as an MR probe. In a model of transgenic a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3682497/ https://ncbi.nlm.nih.gov/pubmed/23575993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.112.115402 |
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