Refinement of atomic models in high resolution EM reconstructions using Flex-EM and local assessment

As the resolutions of Three Dimensional Electron Microscopic reconstructions of biological macromolecules are being improved, there is a need for better fitting and refinement methods at high resolutions and robust approaches for model assessment. Flex-EM/MODELLER has been used for flexible fitting...

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Veröffentlicht in:Methods
Hauptverfasser: Joseph, Agnel Praveen, Malhotra, Sony, Burnley, Tom, Wood, Chris, Clare, Daniel K., Winn, Martyn, Topf, Maya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Academic Press 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854230/
https://ncbi.nlm.nih.gov/pubmed/26988127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.03.007
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