Y402H Polymorphism of Complement Factor H Affects Binding Affinity to C-Reactive Protein()

Complement factor H (FH) is an important regulator of the alternative complement pathway. The Y402H polymorphism within the seventh short consensus repeat of FH was recently shown to be associated with age-related macular degeneration, the most common cause of irreversible blindness in the Western w...

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Publicat a:J Immunol
Autors principals: Laine, Matti, Jarva, Hanna, Seitsonen, Sanna, Haapasalo, Karita, Lehtinen, Markus J., Lindeman, Nina, Anderson, Don H., Johnson, Patrick T., Järvelä, Irma, Jokiranta, T. Sakari, Hageman, Gregory S., Immonen, Ilkka, Meri, Seppo
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853917/
https://ncbi.nlm.nih.gov/pubmed/17339482
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