Multifactor Effects and Evidence of Potential Interaction between Complement Factor H Y402H and LOC387715 A69S in Age-Related Macular Degeneration

BACKGROUND: Variants in the complement cascade genes and the LOC387715/HTRA1, have been widely reported to associate with age-related macular degeneration (AMD), the most common cause of visual impairment in industrialized countries. METHODS/PRINCIPAL FINDINGS: We investigated the association betwee...

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Detalhes bibliográficos
Main Authors: Seitsonen, Sanna P., Onkamo, Päivi, Peng, Gang, Xiong, Momiao, Tommila, Petri V., Ranta, Päivi H., Holopainen, Juha M., Moilanen, Jukka A., Palosaari, Tapani, Kaarniranta, Kai, Meri, Seppo, Immonen, Ilkka R., Järvelä, Irma E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585793/
https://ncbi.nlm.nih.gov/pubmed/19048105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003833
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