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Relevance of HCN2-expressing human mesenchymal stem cells for the generation of biological pacemakers
BACKGROUND: The transfection of human mesenchymal stem cells (hMSCs) with the hyperpolarization-activated cyclic nucleotide-gated ion channel 2 (HCN2) gene has been demonstrated to provide biological pacing in dogs with complete heart block. The mechanism appears to be the generation of the ion curr...
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| Publicat a: | Stem Cell Res Ther |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4853868/ https://ncbi.nlm.nih.gov/pubmed/27137910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-016-0326-z |
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