Extracellular [Formula: see text] is sensed by mouse cerebral arteries: Regulation of tone by receptor protein tyrosine phosphatase γ

We investigate sensing and signaling mechanisms for H(+), [Formula: see text] and CO(2) in basilar arteries using out-of-equilibrium solutions. Selectively varying pH(o), [[Formula: see text]](o,) or pCO(2), we find: (a) lowering pH(o) attenuates vasoconstriction and vascular smooth muscle cell (VSM...

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Publicado en:J Cereb Blood Flow Metab
Autores principales: Boedtkjer, Ebbe, Hansen, Kristoffer B, Boedtkjer, Donna MB, Aalkjaer, Christian, Boron, Walter F
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2015
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853837/
https://ncbi.nlm.nih.gov/pubmed/26661205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X15610787
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