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Role of Receptor Protein Tyrosine Phosphatase γ in Sensing Extracellular CO(2) and HCO(3)(−)

Regulation of blood pH—critical for virtually every facet of life—requires that the renal proximal tubule (PT) adjust its rate of H(+) secretion (nearly the same as the rate of HCO(3)(−) reabsorption, J(HCO(3))) in response to changes in blood [CO(2)] and [HCO(3)(−)]. Yet CO(2)/HCO(3)(−) sensing mec...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Main Authors: Zhou, Yuehan, Skelton, Lara A., Xu, Lumei, Chandler, Margaret P., Berthiaume, Jessica M., Boron, Walter F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004642/
https://ncbi.nlm.nih.gov/pubmed/26839367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015040439
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