Ceramide-CD300f binding suppresses experimental colitis by inhibiting ATP-mediated mast cell activation

OBJECTIVE: Extracellular ATP mediates mast cell-dependent intestinal inflammation via P2X7 purinoceptors. We have previously shown that CD300f (also called the leucocyte mono-immunoglobulin-like receptor 3 (LMIR3)) suppresses immunoglobulin E-dependent and mast cell-dependent allergic responses by b...

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Detalles Bibliográficos
Publicado en:Gut
Main Authors: Matsukawa, Toshihiro, Izawa, Kumi, Isobe, Masamichi, Takahashi, Mariko, Maehara, Akie, Yamanishi, Yoshinori, Kaitani, Ayako, Okumura, Ko, Teshima, Takanori, Kitamura, Toshio, Kitaura, Jiro
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2016
Assuntos:
Inflammatory Bowel Disease
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853571/
https://ncbi.nlm.nih.gov/pubmed/25673319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-308900
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