Synergy Between Gα(z) Deficiency and GLP-1 Analog Treatment in Preserving Functional β-Cell Mass in Experimental Diabetes

A defining characteristic of type 1 diabetes mellitus (T1DM) pathophysiology is pancreatic β-cell death and dysfunction, resulting in insufficient insulin secretion to properly control blood glucose levels. Treatments that promote β-cell replication and survival, thus reversing the loss of β-cell ma...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Brill, Allison L., Wisinski, Jaclyn A., Cadena, Mark T., Thompson, Mary F., Fenske, Rachel J., Brar, Harpreet K., Schaid, Michael D., Pasker, Renee L., Kimple, Michelle E.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853566/
https://ncbi.nlm.nih.gov/pubmed/27049466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1164
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