Synergy Between Gα(z) Deficiency and GLP-1 Analog Treatment in Preserving Functional β-Cell Mass in Experimental Diabetes

A defining characteristic of type 1 diabetes mellitus (T1DM) pathophysiology is pancreatic β-cell death and dysfunction, resulting in insufficient insulin secretion to properly control blood glucose levels. Treatments that promote β-cell replication and survival, thus reversing the loss of β-cell ma...

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Dettagli Bibliografici
Pubblicato in:Mol Endocrinol
Autori principali: Brill, Allison L., Wisinski, Jaclyn A., Cadena, Mark T., Thompson, Mary F., Fenske, Rachel J., Brar, Harpreet K., Schaid, Michael D., Pasker, Renee L., Kimple, Michelle E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2016
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853566/
https://ncbi.nlm.nih.gov/pubmed/27049466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1164
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