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Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells

Spermatogonial stem and progenitor cells (SSCs) generate adult male gametes. During in vitro expansion, these unipotent murine cells spontaneously convert to multipotent adult spermatogonial-derived stem cells (MASCs). Here we investigate this conversion process through integrative transcriptomic an...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Liu, Ying, Giannopoulou, Eugenia G., Wen, Duancheng, Falciatori, Ilaria, Elemento, Olivier, Allis, C. David, Rafii, Shahin, Seandel, Marco
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853422/
https://ncbi.nlm.nih.gov/pubmed/27117588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11275
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