The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma

The REL gene, encoding the NF-κB subunit c-Rel, is frequently amplified in B-cell lymphoma and functions as a tumour-promoting transcription factor. Here we report the surprising result that c-rel–/– mice display significantly earlier lymphomagenesis in the c-Myc driven, Eμ-Myc model of B-cell lymph...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Hunter, J E, Butterworth, J A, Zhao, B, Sellier, H, Campbell, K J, Thomas, H D, Bacon, C M, Cockell, S J, Gewurz, B E, Perkins, N D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853301/
https://ncbi.nlm.nih.gov/pubmed/26522720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.399
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