A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males

BACKGROUND: The mesolimbic dopamine system, composed primarily of dopaminergic neurons in the ventral tegmental area that project to striatal structures, is considered to be the key mediator of reinforcement-related mechanisms in the brain. Prompted by a genome-wide association meta-analysis implica...

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Detalhes bibliográficos
Publicado no:J Psychiatry Neurosci
Main Authors: Stacey, David, Lourdusamy, Anbarasu, Ruggeri, Barbara, Maroteaux, Matthieu, Jia, Tianye, Cattrell, Anna, Nymberg, Charlotte, Banaschewski, Tobias, Bhattacharyya, Sohinee, Band, Hamid, Barker, Gareth, Bokde, Arun, Buchel, Christian, Carvalho, Fabiana, Conrod, Patricia, Desrivieres, Sylvane, Easton, Alanna, Fauth-Buehler, Mira, Fernandez-Medarde, Alberto, Flor, Herta, Frouin, Vincent, Gallinat, Jurgen, Garavanh, Hugh, Heinz, Andreas, Ittermann, Bernd, Lathrop, Mark, Lawrence, Claire, Loth, Eva, Mann, Karl, Martinot, Jean-Luc, Nees, Frauke, Paus, Tomas, Pausova, Zdenka, Rietschel, Marcella, Rotter, Andrea, Santos, Eugenio, Smolka, Michael, Sommer, Wolfgang, Mameli, Manuel, Spanagel, Rainer, Girault, Jean-Antoine, Mueller, Christian, Schumann, Gunter
Formato: Artigo
Idioma:Inglês
Publicado em: Joule Inc. 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853210/
https://ncbi.nlm.nih.gov/pubmed/26679926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.150138
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