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Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents
BACKGROUND: Nociceptin is a key regulator linking environmental stress and alcohol drinking. In a genome-wide methylation analysis we recently identified an association of a methylated region in the OPRL1 gene with alcohol-use disorders. METHODS: Here we investigate the biological basis of this obse...
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| 出版年: | J Child Psychol Psychiatry |
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5975104/ https://ncbi.nlm.nih.gov/pubmed/29197086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcpp.12843 |
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