Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents

BACKGROUND: Nociceptin is a key regulator linking environmental stress and alcohol drinking. In a genome-wide methylation analysis we recently identified an association of a methylated region in the OPRL1 gene with alcohol-use disorders. METHODS: Here we investigate the biological basis of this obse...

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書誌詳細
出版年:J Child Psychol Psychiatry
主要な著者: Ruggeri, Barbara, Macare, Christine, Stopponi, Serena, Jia, Tianye, Carvalho, Fabiana M., Robert, Gabriel, Banaschewski, Tobias, Bokde, Arun LW, Bromberg, Uli, Büchel, Christian, Cattrell, Anna, Conrod, Patricia J, Desrivières, Sylvane, Flor, Herta, Frouin, Vincent, Gallinat, Jürgen, Garavan, Hugh, Gowland, Penny, Heinz, Andreas, Ittermann, Bernd, Martinot, Jean Luc, Paillère Martinot, Marie-Laure, Nees, Frauke, Papadopoulos-Orfanos, Dimitri, Paus, Tomáš, Poustka, Luise, Smolka, Michael N, Vetter, Nora C., Walter, Henrik, Whelan, Robert, Sommer, Wolfgang H, Bakalkin, Georgy, Ciccocioppo, Roberto, Schumann, Gunter
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975104/
https://ncbi.nlm.nih.gov/pubmed/29197086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcpp.12843
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