CCN1 (CYR61) and CCN3 (NOV) signaling drives human trophoblast cells into senescence and stimulates migration properties

During placental development, continuous invasion of trophoblasts into the maternal compartment depends on the support of proliferating extravillous trophoblasts (EVTs). Unlike tumor cells, EVTs escape from the cell cycle before invasion into the decidua and spiral arteries. This study focused on th...

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Dettagli Bibliografici
Pubblicato in:Cell Adh Migr
Autori principali: Kipkeew, Friederike, Kirsch, Manuela, Klein, Diana, Wuelling, Manuela, Winterhager, Elke, Gellhaus, Alexandra
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853050/
https://ncbi.nlm.nih.gov/pubmed/26744771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2016.1139265
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