CCN1 (CYR61) and CCN3 (NOV) signaling drives human trophoblast cells into senescence and stimulates migration properties

During placental development, continuous invasion of trophoblasts into the maternal compartment depends on the support of proliferating extravillous trophoblasts (EVTs). Unlike tumor cells, EVTs escape from the cell cycle before invasion into the decidua and spiral arteries. This study focused on th...

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Detalhes bibliográficos
Publicado no:Cell Adh Migr
Main Authors: Kipkeew, Friederike, Kirsch, Manuela, Klein, Diana, Wuelling, Manuela, Winterhager, Elke, Gellhaus, Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853050/
https://ncbi.nlm.nih.gov/pubmed/26744771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2016.1139265
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