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Conditional mutation of Smc5 in mouse embryonic stem cells perturbs condensin localization and mitotic progression
Correct duplication of stem cell genetic material and its appropriate segregation into daughter cells are requisites for tissue, organ and organism homeostasis. Disruption of stem cell genomic integrity can lead to developmental abnormalities and cancer. Roles of the Smc5/6 structural maintenance of...
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| Yayımlandı: | J Cell Sci |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Company of Biologists Ltd
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4852767/ https://ncbi.nlm.nih.gov/pubmed/26919979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.179036 |
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