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Conditional mutation of Smc5 in mouse embryonic stem cells perturbs condensin localization and mitotic progression
Correct duplication of stem cell genetic material and its appropriate segregation into daughter cells are requisites for tissue, organ and organism homeostasis. Disruption of stem cell genomic integrity can lead to developmental abnormalities and cancer. Roles of the Smc5/6 structural maintenance of...
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| Vydáno v: | J Cell Sci |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Company of Biologists Ltd
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4852767/ https://ncbi.nlm.nih.gov/pubmed/26919979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.179036 |
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