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Transmembrane protein TMEM170A is a newly discovered regulator of ER and nuclear envelope morphogenesis in human cells

The mechanism of endoplasmic reticulum (ER) morphogenesis is incompletely understood. ER tubules are shaped by the reticulons (RTNs) and DP1/Yop1p family members, but the mechanism of ER sheet formation is much less clear. Here, we characterize TMEM170A, a human transmembrane protein, which localize...

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Publicat a:J Cell Sci
Autors principals: Christodoulou, Andri, Santarella-Mellwig, Rachel, Santama, Niovi, Mattaj, Iain W.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852765/
https://ncbi.nlm.nih.gov/pubmed/26906412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.175273
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