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Grainyhead-like 2 downstream targets act to suppress epithelial-to-mesenchymal transition during neural tube closure
The transcription factor grainyhead-like 2 (GRHL2) is expressed in non-neural ectoderm (NNE) and Grhl2 loss results in fully penetrant cranial neural tube defects (NTDs) in mice. GRHL2 activates expression of several epithelial genes; however, additional molecular targets and functional processes re...
Gorde:
| Argitaratua izan da: | Development |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Company of Biologists Ltd
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4852492/ https://ncbi.nlm.nih.gov/pubmed/26903501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.129825 |
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