Llwytho...

Pretargeted Immuno-PET of Pancreatic Cancer: Overcoming Circulating Antigen and Internalized Antibody to Reduce Radiation Doses

5B1 is a fully human, monoclonal antibody that has shown promise for the PET imaging of cancers expressing carbohydrate antigen 19.9 (CA19.9)—a carbohydrate prevalent in cells with aberrant glycosylation and an established effector of metastasis. The long physiologic half-life of the antibody and in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Nucl Med
Prif Awduron: Houghton, Jacob L., Zeglis, Brian M., Abdel-Atti, Dalya, Sawada, Ritsuko, Scholz, Wolfgang W., Lewis, Jason S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852470/
https://ncbi.nlm.nih.gov/pubmed/26471693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.115.163824
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