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Pretargeted Immuno-PET of Pancreatic Cancer: Overcoming Circulating Antigen and Internalized Antibody to Reduce Radiation Doses

5B1 is a fully human, monoclonal antibody that has shown promise for the PET imaging of cancers expressing carbohydrate antigen 19.9 (CA19.9)—a carbohydrate prevalent in cells with aberrant glycosylation and an established effector of metastasis. The long physiologic half-life of the antibody and in...

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Podrobná bibliografie
Vydáno v:J Nucl Med
Hlavní autoři: Houghton, Jacob L., Zeglis, Brian M., Abdel-Atti, Dalya, Sawada, Ritsuko, Scholz, Wolfgang W., Lewis, Jason S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852470/
https://ncbi.nlm.nih.gov/pubmed/26471693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.115.163824
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