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Pretargeted Immuno-PET of Pancreatic Cancer: Overcoming Circulating Antigen and Internalized Antibody to Reduce Radiation Doses

5B1 is a fully human, monoclonal antibody that has shown promise for the PET imaging of cancers expressing carbohydrate antigen 19.9 (CA19.9)—a carbohydrate prevalent in cells with aberrant glycosylation and an established effector of metastasis. The long physiologic half-life of the antibody and in...

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Dades bibliogràfiques
Publicat a:J Nucl Med
Autors principals: Houghton, Jacob L., Zeglis, Brian M., Abdel-Atti, Dalya, Sawada, Ritsuko, Scholz, Wolfgang W., Lewis, Jason S.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852470/
https://ncbi.nlm.nih.gov/pubmed/26471693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.115.163824
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