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A closed conformation of the Caenorhabditis elegans separase–securin complex

The protease separase plays a key role in sister chromatid disjunction and centriole disengagement. To maintain genomic stability, separase activity is strictly regulated by binding of an inhibitory protein, securin. Despite its central role in cell division, the separase and securin complex is poor...

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Bibliographic Details
Published in:Open Biol
Main Authors: Bachmann, Gudrun, Richards, Mark W., Winter, Anja, Beuron, Fabienne, Morris, Edward, Bayliss, Richard
Format: Artigo
Language:Inglês
Published: The Royal Society 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852461/
https://ncbi.nlm.nih.gov/pubmed/27249343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160032
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