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A closed conformation of the Caenorhabditis elegans separase–securin complex

The protease separase plays a key role in sister chromatid disjunction and centriole disengagement. To maintain genomic stability, separase activity is strictly regulated by binding of an inhibitory protein, securin. Despite its central role in cell division, the separase and securin complex is poor...

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Veröffentlicht in:Open Biol
Hauptverfasser: Bachmann, Gudrun, Richards, Mark W., Winter, Anja, Beuron, Fabienne, Morris, Edward, Bayliss, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852461/
https://ncbi.nlm.nih.gov/pubmed/27249343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160032
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