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DNA damage response (DDR) pathway engagement in cisplatin radiosensitization of non-small cell lung cancer

Non-small cell lung cancers (NSCLC) are commonly treated with a platinum-based chemotherapy such as cisplatin (CDDP) in combination with ionizing radiation (IR). Although clinical trials have demonstrated that the combination of CDDP and IR appear to be synergistic in terms of therapeutic efficacy,...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Sears, Catherine R., Cooney, Sean A., Chin-Sinex, Helen, Mendonca, Marc S., Turchi, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852375/
https://ncbi.nlm.nih.gov/pubmed/26991853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.02.004
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