The effect of everolimus on renal angiomyolipoma in patients with tuberous sclerosis complex being treated for subependymal giant cell astrocytoma: subgroup results from the randomized, placebo-controlled, Phase 3 trial EXIST-1

BACKGROUND: Tuberous sclerosis complex (TSC) is characterized by benign tumours in multiple organs, including the brain, kidneys, skin, lungs and heart. Our objective was to evaluate everolimus, an mTOR inhibitor, in the treatment of angiomyolipoma in patients with subependymal giant cell astrocytom...

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Detalhes bibliográficos
Publicado no:Nephrol Dial Transplant
Main Authors: Kingswood, J. Chris, Jozwiak, Sergiusz, Belousova, Elena D., Frost, Michael D., Kuperman, Rachel A., Bebin, E. Martina, Korf, Bruce R., Flamini, J. Robert, Kohrman, Michael H., Sparagana, Steven P., Wu, Joyce Y., Brechenmacher, Thomas, Stein, Karen, Berkowitz, Noah, Bissler, John J., Franz, David N.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
CLINICAL SCIENCE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852219/
https://ncbi.nlm.nih.gov/pubmed/24729041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfu013
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