HSP27 Inhibits Homocysteine-Induced Endothelial Apoptosis by Modulation of ROS Production and Mitochondrial Caspase-Dependent Apoptotic Pathway

Objectives. Elevated plasma homocysteine (Hcy) could lead to endothelial dysfunction and is viewed as an independent risk factor for atherosclerosis. Heat shock protein 27 (HSP27), a small heat shock protein, is reported to exert protective effect against atherosclerosis. This study aims to investig...

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Vydáno v:Biomed Res Int
Hlavní autoři: Tian, Xin, Zhao, Lei, Song, Xianjing, Yan, Youyou, Liu, Ning, Li, Tianyi, Yan, Bingdi, Liu, Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852127/
https://ncbi.nlm.nih.gov/pubmed/27190988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4847874
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