15-Deoxy-Δ(12,14)-prostaglandin J(2) Induces Apoptosis and Upregulates SOCS3 in Human Thyroid Cancer Cells

The cyclopentenone prostaglandin 15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) is a natural ligand of peroxisome proliferator-activated receptor gamma (PPAR-γ) and a potential mediator of apoptosis in cancer cells. In the present study, we evaluated the effect of 15d-PGJ(2) in human thyroid papi...

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Udgivet i:PPAR Res
Main Authors: Trindade-da-Silva, Carlos Antônio, Reis, Carolina Fernandes, Vecchi, Lara, Napimoga, Marcelo Henrique, Sperandio, Marcelo, Matias Colombo, Bruna França, Alves, Patrícia Terra, Ward, Laura Sterian, Ueira-Vieira, Carlos, Goulart, Luiz Ricardo
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852108/
https://ncbi.nlm.nih.gov/pubmed/27190500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4106297
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