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Safety and efficacy of LY3015014, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 (PCSK9): a randomized, placebo-controlled Phase 2 study

AIMS: The objective of this study was to evaluate the efficacy, safety, and tolerability of LY3015014 (LY), a neutralizing antibody of proprotein convertase subtilisin/kexin type 9 (PCSK9), administered every 4 or 8 weeks in patients with primary hypercholesterolaemia, when added to a background of...

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Detalhes bibliográficos
Publicado no:Eur Heart J
Main Authors: Kastelein, John J.P., Nissen, Steven E., Rader, Daniel J., Hovingh, G. Kees, Wang, Ming-Dauh, Shen, Tong, Krueger, Kathryn A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852062/
https://ncbi.nlm.nih.gov/pubmed/26757788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehv707
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