In vivo quantification of demyelination and recovery using compartment-specific diffusion MRI metrics validated by electron microscopy

There is a need for accurate quantitative non-invasive biomarkers to monitor myelin pathology in vivo and distinguish myelin changes from other pathological features including inflammation and axonal loss. Conventional MRI metrics such as T(2), magnetization transfer ratio and radial diffusivity hav...

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Publicado en:Neuroimage
Main Authors: Jelescu, Ileana O., Zurek, Magdalena, Winters, Kerryanne V., Veraart, Jelle, Rajaratnam, Anjali, Kim, Nathanael S., Babb, James S., Shepherd, Timothy M., Novikov, Dmitry S., Kim, Sungheon G., Fieremans, Els
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851889/
https://ncbi.nlm.nih.gov/pubmed/26876473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2016.02.004
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