In vivo quantification of demyelination and recovery using compartment-specific diffusion MRI metrics validated by electron microscopy

There is a need for accurate quantitative non-invasive biomarkers to monitor myelin pathology in vivo and distinguish myelin changes from other pathological features including inflammation and axonal loss. Conventional MRI metrics such as T(2), magnetization transfer ratio and radial diffusivity hav...

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Veröffentlicht in:Neuroimage
Hauptverfasser: Jelescu, Ileana O., Zurek, Magdalena, Winters, Kerryanne V., Veraart, Jelle, Rajaratnam, Anjali, Kim, Nathanael S., Babb, James S., Shepherd, Timothy M., Novikov, Dmitry S., Kim, Sungheon G., Fieremans, Els
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851889/
https://ncbi.nlm.nih.gov/pubmed/26876473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2016.02.004
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