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Elevated TNF-α is associated with pain and physical disability in mucopolysaccharidosis types I, II, and VI

BACKGROUND: Children and adults with the lysosomal storage diseases mucopolysaccharidosis (MPS) types I, II and VI live shortened lives permeated by chronic pain and physical disability. Current treatments do not alleviate these problems. Thus there is a critical need to understand the mechanism of...

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Detalhes bibliográficos
Publicado no:Mol Genet Metab
Main Authors: Polgreen, Lynda E., Vehe, Richard K., Rudser, Kyle, Kunin-Batson, Alicia, Utz, Jeanine Jarnes, Dickson, Patricia, Shapiro, Elsa, Whitley, Chester B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851859/
https://ncbi.nlm.nih.gov/pubmed/26873528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2016.01.012
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