Actions of a Series of PPADS Analogs at P2X(1) and P2X(3) Receptors

[Table: see text] Seven PPADS (Pyridoxal-5′-Phosphate 6-Azophenyl 2′,4′-DiSulfonate) analogs were investigated at Group 1 P2X receptors expressed in Xenopus oocytes. All seven analogs potently inhibited P2X(1) (IC(50) range, 5–32 nM) and P2X(3) (IC(50) range, 22–345 nM), the two Group I P2X receptor...

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Vydáno v:Drug Dev Res
Hlavní autoři: Brown, Sean G., Kim, Yong-Chul, Kim, Soon-Ai, Jacobson, Kenneth A., Burnstock, Geoffrey, King, Brian F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2001
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851439/
https://ncbi.nlm.nih.gov/pubmed/27134334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ddr.1197
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