A novel role for synaptic acetylcholinesterase as an apoptotic deoxyribonuclease

In addition to terminating neurotransmission by hydrolyzing acetylcholine, synaptic acetylcholinesterase (AChE(S)) has been found to have a pro-apoptotic role. However, the underlying mechanism has rarely been investigated. Here, we report a nuclear translocation-dependent role for AChE(S) as an apo...

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Publicado en:Cell Discov
Autores principales: Du, Aiying, Xie, Jing, Guo, Kaijie, Yang, Lei, Wan, Yihan, OuYang, Qi, Zhang, Xuejin, Niu, Xin, Lu, Lu, Wu, Jun, Zhang, Xuejun
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851313/
https://ncbi.nlm.nih.gov/pubmed/27462404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.2
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