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Interaction of Acetylcholinesterase with Neurexin-1β regulates Glutamatergic Synaptic stability in Hippocampal neurons

BACKGROUND: Excess expression of acetylcholinesterase (AChE) in the cortex and hippocampus causes a decrease in the number of glutamatergic synapses and alters the expression of neurexin and neuroligin, trans-synaptic proteins that control synaptic stability. The molecular sequence and three-dimensi...

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Detalhes bibliográficos
Main Authors: Xiang, Yun-Yan, Dong, Haiheng, Yang, Burton B, MacDonald, John F, Lu, Wei-Yang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973991/
https://ncbi.nlm.nih.gov/pubmed/24594013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-7-15
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