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Retinal glial responses to optic nerve crush are attenuated in Bax-deficient mice and modulated by purinergic signaling pathways

BACKGROUND: Retinal ganglion cell (RGC) soma death is a consequence of optic nerve damage, including in optic neuropathies like glaucoma. The activation of the innate immune network in the retina after nerve damage has been linked to RGC pathology. Since the eye is immune privileged, innate immune f...

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書目詳細資料
發表在:J Neuroinflammation
Main Authors: Mac Nair, Caitlin E., Schlamp, Cassandra L., Montgomery, Angela D., Shestopalov, Valery I., Nickells, Robert W.
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850653/
https://ncbi.nlm.nih.gov/pubmed/27126275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0558-y
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