Retinal glial responses to optic nerve crush are attenuated in Bax-deficient mice and modulated by purinergic signaling pathways

BACKGROUND: Retinal ganglion cell (RGC) soma death is a consequence of optic nerve damage, including in optic neuropathies like glaucoma. The activation of the innate immune network in the retina after nerve damage has been linked to RGC pathology. Since the eye is immune privileged, innate immune f...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Mac Nair, Caitlin E., Schlamp, Cassandra L., Montgomery, Angela D., Shestopalov, Valery I., Nickells, Robert W.
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850653/
https://ncbi.nlm.nih.gov/pubmed/27126275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0558-y
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